When your first find a new vacation spot you see it through the eyes of a child. After traveling there for multiple years and seeing changes and some which you may not like you see it as an adult.
My 2 cents is that I think anytime you travel to the same location year after year, there is a certain amount of burn out that develops. Also mentioned in this thread if you develop personal relationships with the folks where you vacation (hard not to if you frequent) they can at times add drama and let you down.
I only get one vacation a year and don't want anything but vacation. Isla Mujeres provided this for 9 years and now Negril is providing the same. First trip to Negril we stayed at CoCo (nice hotel) and I really didn't like the amount of hagglers on the beach. We went to Point Village last year and it was great we could walk long beach but then return to peace and quiet at night and during our beach days no hagglers.
Half Moon is also a nice place get away from the hassle. Going to try Rhodes Hall this year treating as a day trip and don't expect any hassle there.
I am sure at some point I will burn out in Negril but for now it is a nice vacation place. Also for you folks that are enjoying Isla (great place) also keep in mind the close locations of Akumal and Tulum when you burn out on Isla Mujeres (which can become a "Peyton Place" when you get familiar/friends with locals and expats on the island)
Again just my 2 cents
BTW, Isla will provide it again I just needed a break and maybe that is all you need from Negril. Porty, Treasure beach, here I come, when I am retired and have more time to vacation in Jamaica.